Positioned at Mühlenstraße 31, the hotel places guests within walking distance of key attractions. The renowned shopping street, Königsallee, is just a short stroll away, offering a plethora of luxury boutiques and dining options. Cultural enthusiasts will appreciate the proximity to the Kunsthalle gallery and the German Opera on the Rhine, both easily accessible for a dose of art and performance.

Housed in a historic, heritage-listed building, the Living Hotel De Medici exudes an ambiance reminiscent of a museum. Guests can admire a curated collection of sculptures, paintings, and artifacts displayed throughout the premises, creating an immersive cultural experience. The interior architecture harmoniously combines classic elements with contemporary design, ensuring both comfort and aesthetic pleasure.

Each air-conditioned room is thoughtfully designed, featuring a seating area, cable TV, and a private bathroom equipped with modern fixtures. Select rooms offer kitchenettes, catering to guests seeking extended stays or added convenience. The hotel boasts a range of facilities, including a spa and fitness center for relaxation and wellness. Culinary delights await at the on-site restaurant, and the bar provides a cozy setting for evening unwinding. Additional services such as a 24-hour reception, airport transportation, and valet parking enhance the overall guest experience.

Travelers frequently commend the hotel's unique blend of art and hospitality. One guest described it as a "perfect place to explore Düsseldorf and the Altstadt," highlighting the convenient location and exceptional service. Another reviewer appreciated the "comfortable and high-quality" accommodations, noting the hotel's proximity to shopping streets and markets. The fusion of historical charm with modern amenities leaves a lasting impression on visitors, making it a preferred choice for both leisure and business travelers.